Biological & Soft Matter Seminar: Programmable on-chip DNA compartments as artificial cells

Roy Bar-Ziv, WIS

14 May 2014, 11:00 
Shenkar Physics Building, Room 222 
Biological & Soft Matter Seminar

Abstract:

​Programmable on-chip DNA compartments as artificial cells We report assembly of silicon-fabricated, two-dimensional DNA compartments capable of metabolism, programmable protein synthesis, and communication. Metabolism is maintained by continuous diffusion of nutrients and products through a thin capillary, connecting protein synthesis in the DNA compartment with the environment. We programmed fundamental cellular functions including the self-regulation and periodic cycles of protein levels. Gene expression in the DNA compartment reveals a rich dynamical system that is highly controlled by geometry.

 

Seminar Organiser: Jonathan Schwitzer

 

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